Diana
Published in Bloodo Blog · 4 min read · June 19, 2024
Share
Introduction to HbA1c Test
HbA1c, or glycated hemoglobin, is formed when glucose binds to hemoglobin in red blood cells. This test measures the average blood sugar levels over the past three months, providing a reliable snapshot of long-term glucose management.
Importance of HbA1c Testing
Monitoring HbA1c levels is crucial for:
– Diagnosing Type 2 Diabetes
– Managing glucose control
– Assessing risk for diabetes-related complications
Benefits of HbA1c Testing
– Early Detection: Identify prediabetes and diabetes early.
– Management: Optimize diabetes management.
– Complications Prevention: Reduce the risk of severe complications such as heart disease, nerve damage, and kidney failure.
How It Works
– Sample Collection: Collect a dried blood spot (DBS) sample using a simple finger prick.
– Analysis: Samples are analyzed using high-performance liquid chromatography (HPLC), known for precision and accuracy.
– Results: Receive a detailed report on your glucose levels, helping you understand and manage your health better.
Characteristics of the HbA1c test
How Are HbA1c Results Interpreted?
HbA1c values serve as crucial indicators for diagnosing type 2 diabetes and managing glucose control. These values reflect the average blood sugar levels over the past three months and are vital for understanding long-term glucose management. The associated diagnoses and recommendations based on HbA1c values are detailed in the following Table 1.
Table 1. HbA1c result interpretation guide
Accuracy and Reliability
HbA1c measured in capillary blood dried blood spot (CB DBS) samples were compared to three different sample matrices to assess accuracy. At the time of CB DBS collection, different donors provided other sample types:
– Whole blood EDTA (WB)
– Whole blood DBS (WB DBS)
– Capillary blood EDTA (CB)
Different sample matrix results are plotted against appropriate CB DBS sample results in Figure 1. R² values of each correlation are provided.
Figure 1. The accuracy of HbA1c results
Stability
For 22 days, HbA1c remains stable (%CV < 2 %) on the dried blood spot (DBS) card (Figure 2).
Figure 2. Stability of HbA1c on DBS cards
Repeatability
Between-run repeatability results were obtained for a series of samples by analyzing each sample 10 times in the same day. Coefficient of variation did not exceed 1.23% for all samples (Table 2).
Table 2. Between-Run Repeatability Results for HbA1c Samples
Conclusion
Regular HbA1c testing is a proactive step towards better health management. By understanding your glucose levels, you can take control of your health, prevent complications, and live a healthier life.
Disclaimer While this guide simplifies the technical aspects of our test, we recommend consulting with healthcare professionals for a comprehensive understanding of your NAD levels and overall health.
1. “The relationship between the elevation of haemoglobin A1c level, sleep quality and sleep duration in clinically diagnosed pre-diabetic patients.” Diabetes Vasc Dis Res 19, 14791641211067420.
2. “Effects of Sleep Disorders on Hemoglobin A1c Levels in Type 2 Diabetic Patients.” Chin Med J (Engl) 128, 3292–3297.
3. “A step in the right direction: exploring the effects of aerobic exercise on HbA1c reduction.” Egypt J Intern Med 35, 58.
4. “Dietary patterns and their associations with glycemic control among type 2 diabetic patients in Jazan, Saudi Arabia: A cross-sectional study.” Medicine (Baltimore) 102, e34296.
5. “Dietary fibre for glycaemia control: Towards a mechanistic understanding.” Bioact Carbohydrates Diet Fibre 14, 39–53.
6. “Association of Glycosylated Hemoglobin Levels with Vitamin D Status.” J Clin Med Res 9, 1013–1018.
Bloodo™ HbA1c Test Specifications
Introduction to HbA1c Test
HbA1c, or glycated hemoglobin, is formed when glucose binds to hemoglobin in red blood cells. This test measures the average blood sugar levels over the past three months, providing a reliable snapshot of long-term glucose management.
Importance of HbA1c Testing
Monitoring HbA1c levels is crucial for:
Benefits of HbA1c Testing
How It Works
Characteristics of the HbA1c test
How Are HbA1c Results Interpreted?
HbA1c values serve as crucial indicators for diagnosing type 2 diabetes and managing glucose control. These values reflect the average blood sugar levels over the past three months and are vital for understanding long-term glucose management. The associated diagnoses and recommendations based on HbA1c values are detailed in the following Table 1.
Accuracy and Reliability
HbA1c measured in capillary blood dried blood spot (CB DBS) samples were compared to three different sample matrices to assess accuracy. At the time of CB DBS collection, different donors provided other sample types:
Different sample matrix results are plotted against appropriate CB DBS sample results in Figure 1. R² values of each correlation are provided.
Stability
For 22 days, HbA1c remains stable (%CV < 2 %) on the dried blood spot (DBS) card (Figure 2).
Repeatability
Between-run repeatability results were obtained for a series of samples by analyzing each sample 10 times in the same day. Coefficient of variation did not exceed 1.23% for all samples (Table 2).
Conclusion
Regular HbA1c testing is a proactive step towards better health management. By understanding your glucose levels, you can take control of your health, prevent complications, and live a healthier life.
Disclaimer
While this guide simplifies the technical aspects of our test, we recommend consulting with healthcare professionals for a comprehensive understanding of your NAD levels and overall health.